[et_pb_section fb_built=”1″ _builder_version=”4.23″ _module_preset=”default” custom_padding=”4px||0px|||” global_colors_info=”{}”][et_pb_row _builder_version=”4.23″ _module_preset=”default” module_alignment=”center” custom_margin=”-2px|475px||auto||” custom_padding=”0px|||||” animation_style=”fade” animation_duration=”200ms” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/www.tifrh.res.in\/~kmandal\/wp-content\/uploads\/2024\/08\/Logo_updated.png” title_text=”Logo_updated” _builder_version=”4.23″ _module_preset=”default” custom_margin=”1px||18px|||” custom_padding=”19px|450px||451px||” animation_style=”fade” animation_duration=”350ms” locked=”off” global_colors_info=”{}”][\/et_pb_image][et_pb_image src=”https:\/\/www.tifrh.res.in\/~kmandal\/wp-content\/uploads\/2024\/08\/Website_Homepage_updated.png” title_text=”Website_Homepage_updated” align=”center” _builder_version=”4.23″ _module_preset=”default” min_height=”686.7px” custom_margin=”-13px|||||” custom_padding=”4px|||||” animation_style=”fade” animation_duration=”300ms” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.23″ _module_preset=”default” custom_margin=”|auto|-16px|auto||” custom_padding=”3px||0px|||” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.23″ _module_preset=”default” text_font=”Bellota Text|700|||||||” text_text_color=”#001668″ text_font_size=”18px” header_text_align=”center” text_orientation=”center” width=”61.7%” module_alignment=”center” custom_margin=”12px|-35px|10px|196px||” custom_padding=”7px|5px|45px|3px||false” animation_style=”fade” animation_duration=”200ms” global_colors_info=”{}”]<\/p>\n
“Our laboratory is located at the Tata Institute of Fundamental Research in Hyderabad, India (17\u00b026\u00b4 N, 78\u00b018\u00b4 E). Our research interests lie at the interface of chemistry and biology. We use synthetic organic chemistry, total chemical protein synthesis and protein crystallography to understand and then precisely control the molecular basis of protein function”<\/span><\/p>\n [\/et_pb_text][et_pb_slider _builder_version=”4.23″ _module_preset=”default” background_color=”#FFFFFF” text_orientation=”left” min_height=”319.4px” custom_margin=”-13px||-3px|||” custom_padding=”13px||15px|||” animation_style=”fade” animation_duration=”1700ms” animation_delay=”200ms” animation_repeat=”loop” auto=”on” auto_speed=”6000″ scroll_fade_enable=”on” global_colors_info=”{}”][et_pb_slide heading=”One Milestone Down! ” button_text=”Link” button_link=”https:\/\/www.tifrh.res.in\/~kmandal\/people\/” url_new_window=”on” image=”https:\/\/www.tifrh.res.in\/~kmandal\/wp-content\/uploads\/2025\/09\/trio_synopsis.png” use_bg_overlay=”on” bg_overlay_color=”rgba(0,86,0,0)” use_text_overlay=”off” _builder_version=”4.23″ _module_preset=”default” header_level=”h1″ header_text_align=”center” header_text_color=”#0d35e5″ header_font_size=”24px” header_line_height=”1.8em” body_text_align=”center” background_color=”rgba(196,232,255,0.29)” background_enable_color=”on” custom_button=”on” button_text_size=”14px” button_text_color=”#001fad” button_bg_color=”#FFFFFF” button_border_width=”0px” button_border_radius=”8px” button_alignment=”center” text_orientation=”center” width=”100%” max_width=”100%” box_shadow_style_image=”preset2″ global_colors_info=”{}” sticky_transition=”on”]<\/p>\n Huge congratulations to our trio of scholars\u2014 Vishal,\u00a0<\/span>Arighna <\/span>and Mrinmoy \u2014on successfully presenting their pre-thesis seminars! We’re so proud of your hard work and dedication. Onward to the final defense!<\/span><\/p>\n [\/et_pb_slide][et_pb_slide heading=”Final Milestone Achieved! Well Done, Akash!” button_text=”Link” button_link=”https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.biochem.4c00465″ url_new_window=”on” image=”https:\/\/www.tifrh.res.in\/~kmandal\/wp-content\/uploads\/2025\/09\/Akash_thesis_defense-1.png” use_bg_overlay=”on” bg_overlay_color=”rgba(0,86,0,0)” use_text_overlay=”off” _builder_version=”4.23″ _module_preset=”default” header_level=”h1″ header_text_align=”center” header_text_color=”#0d35e5″ header_font_size=”22.5px” header_line_height=”1.8em” body_text_align=”center” background_color=”rgba(196,232,255,0.29)” background_enable_color=”on” custom_button=”on” button_text_size=”14px” button_text_color=”#001fad” button_bg_color=”#FFFFFF” button_border_width=”0px” button_border_radius=”8px” button_alignment=”center” text_orientation=”center” width=”100%” max_width=”100%” hover_enabled=”0″ box_shadow_style_image=”preset2″ global_colors_info=”{}” sticky_transition=”on” title_text=”Akash_thesis_defense” sticky_enabled=”0″]<\/p>\n Congratulations to Akash on the successful defense of his thesis \u2014 a significant milestone that reflects his hard work, dedication, and excellence.<\/span><\/a><\/p>\n [\/et_pb_slide][et_pb_slide heading=”Echoes from X” button_text=”Link” button_link=”https:\/\/x.com\/NOST_India\/status\/1897270199918977126″ url_new_window=”on” image=”https:\/\/www.tifrh.res.in\/~kmandal\/wp-content\/uploads\/2025\/04\/GlR1Lz2aYAAtx0h.jpg” use_bg_overlay=”on” bg_overlay_color=”rgba(0,86,0,0)” use_text_overlay=”off” _builder_version=”4.23″ _module_preset=”default” header_level=”h1″ header_text_align=”center” header_text_color=”#0d35e5″ header_font_size=”24px” header_line_height=”1.8em” body_text_align=”center” background_color=”rgba(196,232,255,0.29)” background_enable_color=”on” custom_button=”on” button_text_size=”14px” button_text_color=”#001fad” button_bg_color=”#FFFFFF” button_border_width=”0px” button_border_radius=”8px” button_alignment=”center” text_orientation=”center” width=”100%” max_width=”100%” box_shadow_style_image=”preset1″ global_colors_info=”{}” sticky_transition=”on”]<\/p>\n Delivered a talk at <\/span>#NOSTOCC2025<\/a><\/span> on\u00a0“Exploring Reciprocal Chiral Specificity to Inhibit Red Blood Cell Invasion by Malaria Parasites.”\u00a0A step forward in the fight against malaria with precision molecular design.<\/span><\/span><\/p>\n [\/et_pb_slide][et_pb_slide heading=”An Elegant Method of Chemical Protein Synthesis” button_text=”Link” button_link=”https:\/\/doi.org\/10.1002\/advs.202510194″ url_new_window=”on” image=”https:\/\/www.tifrh.res.in\/~kmandal\/wp-content\/uploads\/2025\/09\/highlight-scaled.png” use_bg_overlay=”on” bg_overlay_color=”rgba(0,86,0,0)” use_text_overlay=”off” _builder_version=”4.23″ _module_preset=”default” header_level=”h1″ header_text_align=”center” header_text_color=”#0d35e5″ header_font_size=”24px” header_line_height=”1.8em” body_text_align=”center” background_color=”rgba(196,232,255,0.29)” background_enable_color=”on” custom_button=”on” button_text_size=”14px” button_text_color=”#001fad” button_bg_color=”#FFFFFF” button_border_width=”0px” button_border_radius=”8px” button_alignment=”center” text_orientation=”center” width=”100%” max_width=”100%” link_option_url_new_window=”on” box_shadow_style_image=”preset2″ global_colors_info=”{}” sticky_transition=”on”]<\/p>\n Just published in Advanced Science<\/em>! We introduce a one-pot ligation-desulfurization<\/strong> strategy that streamlines chemical protein synthesis, no intermediate purification, high yields, broad applicability. Ubiquitin, collagen analogue, barstar A, all synthesized with ease.<\/span><\/p>\n [\/et_pb_slide][et_pb_slide heading=”Best Poster Presentation Award” button_text=”Link” button_link=”https:\/\/x.com\/arighna_sarkar\/status\/1896248010776190987″ url_new_window=”on” image=”https:\/\/www.tifrh.res.in\/~kmandal\/wp-content\/uploads\/2025\/09\/Arighna_best_poster-scaled.png” use_bg_overlay=”on” bg_overlay_color=”rgba(0,86,0,0)” use_text_overlay=”off” _builder_version=”4.23″ _module_preset=”default” header_level=”h1″ header_text_align=”center” header_text_color=”#0d35e5″ header_font_size=”24px” header_line_height=”1.8em” body_text_align=”center” background_color=”rgba(196,232,255,0.29)” background_enable_color=”on” custom_button=”on” button_text_size=”14px” button_text_color=”#001fad” button_bg_color=”#FFFFFF” button_border_width=”0px” button_border_radius=”8px” button_alignment=”center” text_orientation=”center” width=”100%” max_width=”100%” link_option_url_new_window=”on” hover_enabled=”0″ box_shadow_style_image=”preset1″ global_colors_info=”{}” sticky_transition=”on” title_text=”Arighna_best_poster” sticky_enabled=”0″]<\/p>\n Congratulations to Arighna Sarkar on receiving the best poster award at the 10th International Peptide Symposium organized by the Indian Peptide Society<\/span><\/p>\n [\/et_pb_slide][et_pb_slide heading=”Best Poster Presentation Award” button_text=”Link” button_link=”https:\/\/x.com\/TIFRH_buzz\/status\/1823688820413612150″ url_new_window=”on” image=”https:\/\/www.tifrh.res.in\/~kmandal\/wp-content\/uploads\/2024\/08\/GU8LTaobgAAcCT9.png” use_bg_overlay=”on” bg_overlay_color=”rgba(0,86,0,0)” use_text_overlay=”off” _builder_version=”4.23″ _module_preset=”default” header_level=”h1″ header_text_align=”center” header_text_color=”#0d35e5″ header_font_size=”24px” header_line_height=”1.8em” body_text_align=”center” background_color=”rgba(196,232,255,0.29)” background_enable_color=”on” custom_button=”on” button_text_size=”14px” button_text_color=”#001fad” button_bg_color=”#FFFFFF” button_border_width=”0px” button_border_radius=”8px” button_alignment=”center” text_orientation=”center” width=”100%” max_width=”100%” box_shadow_style_image=”preset2″ global_colors_info=”{}” sticky_transition=”on”]<\/p>\n Congratulations to Mrinmoy Jana on receiving the best poster award in biochemistry at the ‘Current Trends in Drug Discovery and Advances in Diagnostics: Chemical Biology approaches’, 11th Annual Meeting of Chemical Biology Society-India, held at Adichunchanagiri University, Karnataka.<\/span><\/p>\n [\/et_pb_slide][et_pb_slide heading=”Best Poster Presentation Award” button_text=”Link” url_new_window=”on” image=”https:\/\/www.tifrh.res.in\/~kmandal\/wp-content\/uploads\/2025\/09\/Akash_best_poster_2.png” use_bg_overlay=”on” bg_overlay_color=”rgba(0,86,0,0)” use_text_overlay=”off” _builder_version=”4.23″ _module_preset=”default” header_level=”h1″ header_text_align=”center” header_text_color=”#0d35e5″ header_font_size=”24px” header_line_height=”1.8em” body_text_align=”center” background_color=”rgba(196,232,255,0.29)” background_enable_color=”on” custom_button=”on” button_text_size=”14px” button_text_color=”#001fad” button_bg_color=”#FFFFFF” button_border_width=”0px” button_border_radius=”8px” button_alignment=”center” text_orientation=”center” width=”100%” max_width=”100%” box_shadow_style_image=”preset2″ global_colors_info=”{}” sticky_transition=”on” title_text=”Akash_best_poster_2″]<\/p>\n Congratulations to Akash Narayan for receiving the \u2018Best Poster Award\u2019<\/strong> at the Drug Discovery and Development <\/em>workshop held at the University of Hyderabad.<\/span><\/p>\n [\/et_pb_slide][\/et_pb_slider][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=”4.23″ _module_preset=”default” background_color=”rgba(0,0,0,0.24)” background_image=”https:\/\/www.tifrh.res.in\/~kmandal\/wp-content\/uploads\/2024\/08\/Untitled-design-1.png” background_blend=”luminosity” background_enable_video_mp4=”off” module_alignment=”center” min_height=”227.2px” custom_margin=”72px|auto|72px|auto|true|” custom_padding=”4px||0px|||” animation_style=”fade” animation_duration=”200ms” border_width_all=”1px” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.23″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.23″ _module_preset=”default” text_font=”Bellota Text|300|||||||” background_enable_image=”off” custom_margin=”1px|||||” custom_padding=”30px||0px|||” inline_fonts=”Abyssinica SIL,Bellota Text,Aboreto” global_colors_info=”{}”]<\/p>\n <\/span><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" “Our laboratory is located at the Tata Institute of Fundamental Research in Hyderabad, India (17\u00b026\u00b4 N, 78\u00b018\u00b4 E). Our research interests lie at the interface of chemistry and biology. We use synthetic organic chemistry, total chemical protein synthesis and protein crystallography to understand and then precisely control the molecular basis of protein function”Huge congratulations to […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-448","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.tifrh.res.in\/~kmandal\/wp-json\/wp\/v2\/pages\/448","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.tifrh.res.in\/~kmandal\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.tifrh.res.in\/~kmandal\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.tifrh.res.in\/~kmandal\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.tifrh.res.in\/~kmandal\/wp-json\/wp\/v2\/comments?post=448"}],"version-history":[{"count":86,"href":"https:\/\/www.tifrh.res.in\/~kmandal\/wp-json\/wp\/v2\/pages\/448\/revisions"}],"predecessor-version":[{"id":878,"href":"https:\/\/www.tifrh.res.in\/~kmandal\/wp-json\/wp\/v2\/pages\/448\/revisions\/878"}],"wp:attachment":[{"href":"https:\/\/www.tifrh.res.in\/~kmandal\/wp-json\/wp\/v2\/media?parent=448"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}<\/blockquote>\n
Kalyaneswar Mandal, Ph.D.<\/span><\/strong><\/span><\/h3>\n
Tata Institute of Fundamental Research Hyderabad, India<\/span><\/a><\/span><\/h3>\n
kmandal@tifrh.res.in<\/span><\/span><\/h3>\n
<\/blockquote>\n