“Our laboratory is located at the Tata Institute of Fundamental Research in Hyderabad, India (17°26´ N, 78°18´ E). Our research interests lie at the interface of chemistry and biology. We use synthetic organic chemistry, total chemical protein synthesis and protein crystallography to understand and then precisely control the molecular basis of protein function”

One Milestone Down!

Huge congratulations to our trio of scholars— Vishal, Arighna and Mrinmoy —on successfully presenting their pre-thesis seminars! We’re so proud of your hard work and dedication. Onward to the final defense!

Echoes from X

Delivered a talk at #NOSTOCC2025 on “Exploring Reciprocal Chiral Specificity to Inhibit Red Blood Cell Invasion by Malaria Parasites.” A step forward in the fight against malaria with precision molecular design.

An Elegant Method of Chemical Protein Synthesis

Just published in Advanced Science! We introduce a one-pot ligation-desulfurization strategy that streamlines chemical protein synthesis, no intermediate purification, high yields, broad applicability. Ubiquitin, collagen analogue, barstar A, all synthesized with ease.

Best Poster Presentation Award

Congratulations to Arighna Sarkar on receiving the best poster award at the 10th International Peptide Symposium organized by the Indian Peptide Society

Best Poster Presentation Award

Congratulations to Mrinmoy Jana on receiving the best poster award in biochemistry at the ‘Current Trends in Drug Discovery and Advances in Diagnostics: Chemical Biology approaches’, 11th Annual Meeting of Chemical Biology Society-India, held at Adichunchanagiri University, Karnataka.

Best Poster Presentation Award

Congratulations to Akash Narayan for receiving the ‘Best Poster Award’ at the Drug Discovery and Development workshop held at the University of Hyderabad.

Kalyaneswar Mandal, Ph.D.

Tata Institute of Fundamental Research Hyderabad, India

kmandal@tifrh.res.in